What is the deferent between ADR and ADE.

Dear Fredrick,
This additional part of my report
Please don’t use a lot of titles (subheading)
Make it clear and understandable to the reader
Please add update references.

Medication safety and medicine related problem

Medication safety (MS):
Definitions of medication safety with reference for each definition, at least4 definitions and make sure to include one or more definition from the UK Institute (I need different definition and explanation and what the difference between each definition in critical comment for each definition not only mention the definition, I need to make critical differentiation between each definition and other).
History of medication safety include when they start it and why?
Please add the different concept as pharmaceutical care then patient center approach then medication therapy management until reach medication optimization concept.
Make sure to be do it in order (sequence) according to which concept is star first.
Why the concept is change during the time (critical explanation and comment)
To be reach in the end to the medication optimization ( please write it as a story in correct order, clear and brief)

Medication related problem (MRP)
Definitions of medication safety with reference for each definition, at least4 definitions and make sure to include one or more definition from the UK Institute (I need different definition and explanation and what the difference between each definition in critical comment for each definition not only mention the definition, I need to make critical differentiation between each definition and other).
WHAT is the terminology are using for the MRP in literature.
Types and categories of MRP.
Definition of medication error (ME) AND mention example of error regards anticoagulant ( in the UK)
Detention of adverse drug reaction(ADR) AND mention example of adverse drug reaction regards anticoagulant ( in the UK)

Definition of adverse drug event(ADE) AND mention example of adverse drug event regards anticoagulant ( in the UK)
Please add the diagram of ME , ADR and MRP in suitable place.

What is the deferent between ADR and ADE
Then add the relation between the ME, ADR and ADE with MRP.
What is the classification system of MRP whith advantages and disadvantages of each?
What is Relation of patient with MRP. ( critical explanation please)
What is the relation of health care provider with MRP.( critical explanation please)
I MEAN patient AND health care provider could be one of the causes of MRP.
Prevalence of MRP IN hospitals in the UK and US.
Reporting system of incident or errors and adverse drug reaction in the UK ( for example the yellow card………etc)

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